WARNING: Internet Explorer does not support modern web standards. This site may not function correctly on this browser and is best viewed on Chrome, Firefox or Edge browsers. Learn More.

Vitrectomy, fluid-gas exchange and transforming growth factor–beta-2 for the treatment of traumatic macular holes.



To evaluate whether vitreous surgery is successful in closing full-thickness traumatic macular holes and whether there is subsequent improvement in visual acuity.


Twelve eyes from 12 consecutive patients with traumatic macular holes underwent vitrectomy, fluid-gas exchange and instillation of bovine or recombinant transforming growth factor (TGF)-beta-2. Three of four eyes underwent repeat vitrectomy with TGF-beta-2 after the initial procedure failed to close the macular hole.


Eleven (92%) of 12 eyes had closure of the macular hole. Follow-up ranged from 3 to 33 months. Visual acuity improved by 2 or more lines in 8 (67%) of 12 eyes. Six (50%) of 12 eyes improved to 20/40 or better. All 3 eyes that underwent reoperation had successful closure of the macular hole and achieved 2 or more lines of visual improvement.


Treatment of full-thickness traumatic macular holes with vitrectomy, fluid-gas exchange, and TGF-beta-2 may result in successful anatomic closure and visual improvement.

Click here for more information – http://www.ncbi.nlm.nih.gov/pubmed/9098285

Are You Suffering From Flashes & Floaters?
Schedule a Retina Eye Exam Today!
Patient Portal Login

Our Locations


6325 Woodside Court
Suite 125
Columbia, Maryland 21046

(410) 919-4455
Fax: (410) 339-7326
Mon-Fri: 8:30am to 5:00pm
On Call 24/7 (410) 919-4455

Owings Mills

21 Crossroads Drive
Suite 425
Owings Mills, MD 21117

(410) 337-4500
Fax: (410) 339-7326
Mon-Fri: 8am-4:30pm
On Call 24/7 (410) 337-4500


5420 Olney Laytonsville Road
Olney, MD 20832

(410) 919-4455
Fax: (410) 339-7326
Mon-Fri: 8am-4:30pm
On Call 24/7 (410) 337-4500